InsightAce Analytic Pvt. Ltd. has announced the publication of a market research report titled “Global mRNA Synthesis and Manufacturing Services Market (by Type of Industry (Therapeutics and Vaccine Developers, CDMO Organizations, Custom Synthesis/Other Service Providers), Applications (Infectious Disease Vaccines, Other Vaccines, Therapeutics and Others), Scale of Operation (Research / Preclinical, Clinical, Commercial))- Market Outlook and Industry Analysis 2031” According to company’s newest research, Global mRNA Synthesis and Manufacturing Services Market is worth US$ 53,278.8 Million in 2021 and is predicted to reach US$ 22,634.5 Million in 2031, with a promising CAGR of -3.4% between 2022 and 2031.
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mRNAs are single-stranded nucleic acids that are synthesised from DNA. They play a crucial role in the way that genes are expressed. To perform their clinical function of directing the synthesis of the encoded protein within cells, mRNA molecules should be delivered to the site of clinical action. Messenger RNA (mRNA) is a useful platform for the study and development of therapeutic and preventative vaccines against a wide range of infectious and chronic diseases due to its adaptability and versatility. mRNA vaccines have a higher rate of success, better immunogenicity, and less expensive production costs than other vaccines as compared to conventional medications. For instance, the first two SARS-CoV-2 vaccines were based on mRNA and were approved for use in a number of different international locales. Additionally licenced for use against other viral infections are these vaccinations. The demand for mRNA manufacturing capacity has significantly increased as a direct result of this. mRNA-based therapies are anticipated to be successful treatments for a variety of difficult-to-treat illnesses, including cancer, cardiovascular and cerebrovascular diseases, infectious diseases, metabolic genetic diseases, and others. It’s essential to note that there is no possibility of accidental mRNA infection or accidental insertional mutagenesis. Additionally, because mRNA is continually translated into encoded proteins and peptides that result in long-lasting expression, it offers a greater therapeutic efficacy than conventional proteins and peptide therapies for treating disorders that need protein production.
The rise in prevalence of rare diseases like propionic acidemia, methylmalonic acidemia, glycogen disease, phenylketonuria, metabolic and immunological disorders, as well as chronic diseases like cancer, heart disease, pulmonary, CKD, and others is what is causing the market for mRNA synthesis and manufacturing services to grow. Recent developments in this area of the biopharmaceutical industry imply that service providers are increasing their capabilities and infrastructure to satisfy the demand for this novel class of biologics that is both existing and anticipated. Due to the upward number of clinical studies for the treatment of infectious diseases and cancer, the market for mRNA synthesis and manufacturing services is anticipated to expand rapidly over the next years. Recent industry developments include increasing research and development initiatives, wider mergers and partnerships, and higher investments by operational enterprises. For instance, through a joint venture with Axcelead, Inc., the American mRNA therapeutic developer Arcturus Therapeutics established a Japanese company in Chiba Prefecture in April 2021. Additionally, they are now building a production facility in Minamisoma City, Fukushima Prefecture. It is projected that these investments would have a positive impact on the sector’s future growth.
However, the lack of manufacturing processes that are adaptable, long-lasting, and cost-effective is impeding the growth of mRNA synthesis and manufacturing services. Additionally, the protracted approvals process and prolonged clinical trials will restrain market growth throughout the forecast period.
The availability of significant funding for research, the expansion of federal programmes toward RNA-based therapies, and the rising number of clinical studies will be the primary growth drivers for the mRNA synthesis and manufacturing services market in North America.
Some of the significant market players of the mRNA synthesis and manufacturing services market are Silence Therapeutics, eTheRNA (Etherna Immunotherapies), Eurogentec, Aldevron, biosynthesis, Biomay, miRagen Therapeutics, Inc., APExBIO, TriLink BioTechnologies, Tiba Biotechnology, CELLSCRIPT, Thermo Fisher Scientific, New England Biolabs, Translate Bio, CureVac, Moderna, Ethris (AstraZeneca), Kernal Biologics, In-Cell-Art, Anima Biotch, H3 Biomedicine Inc., Arcturus Therapeutics, BioNTech (Pfizer), Ionis Pharmaceuticals, Inc., Jena Biosciences,Stemirna Therapeutics Co., Ltd., eFFECTOR Therapeutics, Inc., NVRNAimmune (Sirnaomics), Skyhawk Therapeutics, Inc, Ziphius Therapeutics, Strand Therapeutics Inc., and other Prominent Players.
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Important Market Developments
- In Aug 2022, Under the name Faustovirus Capping Enzyme, New England Biolabs® has created a brand-new enzymatic mRNA capping solution for the production of mRNA. The capping efficiency and scalability for mRNA manufacturing workflows, including vaccine production, are improved by this novel enzyme.
- In January 2022, A new global partnership agreement was just inked by Pfizer and BioNTech to collaborate on the creation of the first shingles vaccine based on mRNA. The creation of possible product candidates will make use of both the antigen technology from Pfizer and the unique mRNA technology from BioNTech. Clinical studies are anticipated to start in the second part of 2022.
- In October 2021, Silence Treatments and Hansoh Pharma established a partnership to create therapeutics using Silence’s mRNAi GOLDTM Platform. It is anticipated that Hansoh will pay sixteen million dollars up front, and milestone payments for Silence might reach one billion three hundred million dollars.
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Global MRNA Synthesis and Manufacturing Services Market, by Type of Industry 2022-2031 (Value US$ Mn)
- Therapeutics and Vaccine Developers
- CDMO Organizations
- Custom Synthesis/Other Service Providers
Global MRNA Synthesis and Manufacturing Services Market, by Applications, 2022-2031 (Value US$ Mn)
- Infectious Disease Vaccines
- Other Vaccines
- Therapeutics and Others
Global MRNA Synthesis and Manufacturing Services Market, by Scale of Operation, 2022-2031 (Value US$ Mn)
- Research / Preclinical
Global MRNA Synthesis and Manufacturing Services Market, by Region, 2022-2031 (Value US$ Mn)
- North America
- Asia Pacific
- Latin America
- Middle East & Africa
The North America MRNA Synthesis and Manufacturing Services Market, by Country, 2022-2031 (Value US$ Mn)
Europe MRNA Synthesis and Manufacturing Services Market, by Country, 2022-2031 (Value US$ Mn)
- Rest of Europe
Asia Pacific MRNA Synthesis and Manufacturing Services Market, by Country, 2022-2031 (Value US$ Mn)
- South Korea
- Australia & New Zealand
Latin America MRNA Synthesis and Manufacturing Services Market, by Country, 2022-2031 (Value US$ Mn)
- Rest of Latin America
Middle East & Africa MRNA Synthesis and Manufacturing Services Market, by Country, 2022-2031 (Value US$ Mn)
- GCC Countries
- South Africa
- Rest of Middle East & Africa
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- To evaluate the market dynamics and obstacles for MRNA Synthesis and Manufacturing Services
- To learn more about the market size for MRNA Synthesis and Manufacturing Services (in US$ Mn) projected to 2030
- Significant acquisitions and investments have been made in the MRNA Synthesis and Manufacturing Services market.
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